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Four Ways that Strain Specific Enumeration can Increase Operational Efficiencies for Probiotic Products

Strain specific enumeration can significantly improve operational efficiencies in the production of probiotic products. Enumeration refers to the process of quantifying the number of viable microorganisms in a given sample of a probiotic product. The number of live bacteria present in the product can have a significant impact on its therapeutic benefits.

Strain specific enumeration can improve operational practices in the probiotic industry in these four ways:

  1. 1
    Improved batch-to-batch consistency: by enumerating the number of viable microorganisms in a probiotic product, manufacturers can ensure that each batch contains a consistent number of microorganisms. This can help to improve batch-to-batch consistency and reduce the variability between different batches of the same product.
  2. 2
    Faster product release: strain specific enumeration can help manufacturers release their products more quickly. By confirming that a product meets the required levels of live microorganisms, manufacturers can ensure the product is safe and effective, and ready to release to the market.
  3. 3
    Better product development and optimization: strain specific enumeration can help manufacturers to develop and optimize their products more effectively. By accurately measuring the number of live microorganisms in a product, manufacturers can determine the appropriate dosage needed to achieve the desired health effects.
  4. 4
    Reduced production costs: strain specific enumeration can also help to reduce production costs. By accurately measuring the number of viable microorganisms in a probiotic product, manufacturers can ensure that they are using the right amount of raw materials and reduce wastage.

There are several methods used for the enumeration of probiotics, including plate count methods, flow cytometry, and molecular techniques such as viability-qPCR (v-PCR).

Innovative strain specific enumeration with viability qPCR is used for the analysis of raw material to all different dosage forms of probiotic products for accurate determination of viable counts throughout the shelf life.

Purity-IQ is a leader in strain specific enumeration services and offers enumeration analysis that can be used for single or multi-strain blends, strain specific counts, tyndallized (heat-killed), and next generation probiotics.

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